Nature Genetics publishes the very highest quality research in genetics. It encompasses genetic and functional genomic studies on human traits and on other model organisms, including mouse, fly, nematode and yeast. Current emphasis is on the genetic basis for common and complex diseases and on the functional mechanism, architecture and evolution of gene networks, studied by experimental perturbation.

Integrative genetic topics comprise, but are not limited to:

• Genes in the pathology of human disease
• Molecular analysis of simple and complex genetic traits
• Cancer genetics
• Epigenetics
• Gene therapy
• Developmental genetics
• Regulation of gene expression
• Strategies and technologies for extracting function from genomic data
• Pharmacological genomics
• Genome evolution