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Stroke is the second leading cause of death and a leading cause of disability worldwide. This invaluable reference provides clinicians caring for stroke patients with ready access to the optimal evidence for best practice in stroke prevention, acute stroke treatment, and stroke recovery. Now an edited volume, the editors and authors, many of whom are members of the Cochrane Stroke Review Group, describe all available medical, endovascular, and surgical treatments; the rationale for using them; and the strength of the evidence for their safety and effectiveness. New chapters cover key, rapidly advancing therapeutic topics, including prehospital stroke care and regionalized stroke systems, endovascular reperfusion therapy, and electrical and magnetic brain stimulation to enhance recovery. This is an essential resource for clinicians translating into practice the many dramatic advances that have been made in the treatment and prevention of stroke, and suggesting the most appropriate interventions.
Stroke Prevention and Treatment: An Evidence-based Approach
Part I. Foundations: 1. Stroke: the size of the problem Graeme J. Hankey; 2. Understanding evidence Jeffrey L. Saver and Graeme J. Hankey; Part II. Systems of Care: 3. Prehospital stroke care and regionalized stroke systems Kori Sauser Zachrison and Lee Schwamm; 4. Organized stroke care Peter Langhorne; Part III. Acute Treatment of Ischemic Stroke and Transient Ischemic Attack: 5. Supportive care during acute cerebral ischemia Askiel Bruno, Subhashini Ramesh and Jeffrey L. Saver; 6. Reperfusion of the ischemic brain by intravenous thrombolysis Jeffrey L. Saver and Joanna Wardlaw; 7. Reperfusion of the ischemic brain by endovascular thrombectomy and thrombolysis Meng Lee and Jeffrey L. Saver; 8. Collateral flow enhancement: blood pressure lowering and alteration of blood viscosity Else Sandset and Eivind Berge; 9. Acute antiplatelet therapy for the treatment of ischemic stroke and transient ischemic attack Jeffrey L. Saver; 10. Acute anticoagulant therapy for the treatment of acute ischemic stroke and transient ischemic attack Xinyi Leng and Lawrence Wong; 11. Treatment of brain edema Jeffrey L. Saver and Salvador Cruz-Flores; 12. Neuroprotection for acute brain ishemica Jeffrey L. Saver and Nerses Sanossian; Part IV. Acute Treatment of Hemorrhagic Stroke: 13. Acute treatment of intracerebral hemorrhage Tom Moullaali, Rustam Al-Shahi Salman and Craig Anderson; 14. Acute treatment of subarachnoid hemorrhage Sherri Braksick and Alejandro Rabinstein; Part V. Prevention: 15. Prevention of stroke by lowering blood pressure Meng Lee, Jeffrey L. Saver and Bruce Ovbiagele; 16. Prevention of stroke by lowering blood cholesterol concentrations Maurizio Paciaroni; 17. Prevention of stroke by modification of additional vascular and lifestyle risk-factors Amytis Towfighi and Jeffrey L. Saver; 18. Drugs, devices and procedural therapies to prevent recurrent cardiogenic embolic stroke Graeme J. Hankey; 19. Long-term antithrombotic therapy for large and small artery occlusive disease Graeme J. Hankey; 20. Carotid and vertebral artery revascularization Mandy D. Muller, Leo H. Bonati and Martin M. Brown; 21. Cervical artery dissections and cerebral vasculitis Philippe Lyrer; 22. Prevention of intracerebral and subarachnoid hemorrhage James Klaas and Robert Brown; Part VI. Stroke Rehabilitation and Recovery: 23. Evidence-based motor rehabilitation after stroke Gert Kwakkel and Janne Veerbeek; 24. Language and cognitive rehabilitation after stroke Marian Brady and Jonathan Evans; 25. Using pharmacotherapy to enhance stroke recovery Larry Goldstein; 26. Electrical and magnetic brain stimulation to enhance post-stroke recovery Mark Parsons and Jodie Marquez.