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Intraperitoneal Cancer Therapy: Principles and Practice is one of the first books to combine the latest clinical developments in the treatment of patients with peritoneal surface disease and the scientific principles that underlie the concept of intraperitoneal cancer therapy.
The book covers basic concepts such as anatomy, physiology, pharmacology, and mathematical models of drug transport as well as practical clinical applications, highlighted with results from clinical trials and promising novel preclinical developments.
The book is a state-of-the-art reference for surgical and medical oncologists interested in the treatment of carcinomatosis. It also establishes and promotes basic and translational research interest in the field of intraperitoneal drug delivery, which has the potential to improve the outcome for this dreaded condition. Edited by two renowned surgical oncologists, it represents the definitive reference in the field of intraperitoneal cancer therapy. "The unique feature of this book is its complete coverage of all essentials for treating peritoneal surface malignancies -- it is truly a "one stop shop"... The quality of this book is superb and the digital version provides an extra dimension. It is unique in the comprehensive coverage of this highly specific topic and cannot readily be compared to other books." - Carlos HF Chan, MD, PhD (University of Iowa Hospitals and Clinics), 5 stars, Doody Enterprises
Intraperitoneal Cancer Therapy: Principles and Practice
PERITONEUM: EMBRYOLOGY, ANATOMY, AND PHYSIOLOGY
Embryology and Anatomy of the Peritoneal Cavity
Jesus Esquivel
Structure and Function of the Mesothelial Cell
Steven E. Mutsaers, Cecilia M. Prele, and Sarah E. Herrick
Applied Radiological Anatomy of the Peritoneal Cavity
Katie Planche
Peritoneal Drug Transport
Michael F. Flessner
PERITONEAL CARCINOMATOSIS: BASIC MECHANISMS
Molecular Biology of Peritoneal Carcinomatosis
Riom Kwakman, Nina R. Sluiter, Erienne M.V. de Cuba, and Elisabeth (Lisette) A. te Velde
Dissemination and Adhesion of Peritoneal Cancer Cells to the Peritoneal Wall
Elly De Vlieghere, Marc Bracke, Laurine Verset, Pieter Demetter, and Olivier De Wever
Genomic Approaches to Peritoneal Carcinomatosis
Haroon A. Choudry and David L. Bartlett
Surgery, Wound Healing, and Peritoneal Minimal Residual Disease in Colorectal Cancer
Wim P. Ceelen
Role of the Greater Omentum in the Pathogenesis of Peritoneal Carcinomatosis
Manuel J. Koppe
Lymphatic Transport and the Diaphragmatic Stomata
Katharina G.M.A. D'Herde
INTRAPERITONEAL DRUG THERAPY: BASIC PRINCIPLES
Pharmacokinetics of Intraperitoneal Cytotoxic Drug Therapy
Kurt Van der Speeten
Tissue Transport and Pharmacodynamics of Intraperitoneal Chemotherapy
Pieter Colin, Felix Gremonprez, and Wim P. Ceelen
Mathematical Models of Intraperitoneal Drug Delivery
Joanna Stachowska-Pietka and Jacek Waniewski
SURGICAL TECHNIQUES FOR INTRAPERITONEAL DRUG DELIVERY
Management of Peritoneal Metastases Using Cytoreductive Surgery and Perioperative Chemotherapy
Paul H. Sugarbaker
Chemoperfusion Techniques and Technologies
Kiran Turaga
Port Placement for Intraperitoneal Chemotherapy
Lisa M. Landrum and Joan L. Walker
CLINICAL RESULTS OF INTRAPERITONEAL DRUG DELIVERY
Intraperitoneal Chemotherapy for Ovarian Cancer
Abdulrahman Sinno and Deborah Armstrong
Cytoreductive Surgery and HIPEC in the Treatment of Advanced Epithelial Ovarian Cancer and Serous Papillary Peritoneal Carcinoma
Deraco Marcello, Kusamura Shigeki, and Baratti Dario
Pseudomyxoma Peritonei
Bettina Lieske and Brendan Moran
Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Metastatic Colorectal Cancer with Peritoneal Surface Disease
Edward A. Levine and Chukwuemeka Obiora
Diffuse Malignant Peritoneal Mesothelioma: Current Concepts in Evaluation and Management
Keli M. Turner and H. Richard Alexander, Jr
Gastric Cancer and Intraperitoneal Chemotherapy
Valerie Francescutti, John M. Kane III, and Joseph J. Skitzki
Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Carcinomatosis from Small Bowel Adenocarcinoma
Edward A. Levine
Peritoneal Surface Malignancy from Neuroendocrine Tumors
Mladjan Protic, Itzhak Avital, and Alexander Stojadinovic
Treatment Considerations for High-Grade Appendiceal Adenocarcinoma
Sean P. Dineen, Melissa Taggart, Richard E. Royal, Paul Mansfield, and Keith F. Fournier
Systemic Therapy for Appendiceal Cancer
Jennifer L. Zadlo and Cathy Eng
Toxicity and Morbidity of IP Drug Therapy
Colette Pameijer
Safety Considerations and Occupational Hazards
Joel M. Baumgartner, Kaitlyn J. Kelly, and Andrew M. Lowy
Role of CRS/HIPEC in the Management of Malignant Ascites
Konstantinos I. Votanopoulos
NOVEL AND EXPERIMENTAL APPROACHES
Development of Drug-Loaded Particles for Intraperitoneal Therapy
Ze Lu, M. Guillaume Wientjes, and Jessie L.-S. Au
Biomaterials and Drug Delivery Systems for Intraperitoneal Chemotherapy
Bo Sun and Yoon Yeo
Intraperitoneal Nonviral Nucleic Acid Delivery in the Treatment of Peritoneal Cancer
George R. Dakwar, Stefaan S.C. De Smedt, and Katrien Remaut
Immunotherapy of Peritoneal Carcinomatosis
Michael A. Stroehlein and Markus M. Heiss
The Promise of Oncolytic Viral Therapy for the Treatment of Peritoneal Surface Malignancies
John H. Stewart, IV and Lauren Gillory
Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC)
Marc A. Reymond, W. Solass, and C. Tempfer