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THE DARKEST HOURS by Jim Butcher

When Black Cat foils Spider-Man's attempts to stop the Rhino rampaging through Times Square, she informs him the Rhino is just a distraction. The real threat comes from a group of Ancients, members of the same race as the being called Morlun, seeking revenge for Spider-Man defeating them years before. Spidey must rely on Black Cat if there's any hope of stopping them again, before they can steal his life force

. DOWN THESE MEAN STREETS by Keith R.A. DeCandido

A mysterious drug known as Triple X has been giving users super-powers as well as rendering them mentally and physically unstable. Only by teaming up with a police force that hates him can Spider-Man find the source behind this lethal drug and protect people from those using it. But one of Spider-Man's most fearsome enemies may be behind it all as part of a greater scheme to bring down the city.

DROWNED IN THUNDER by Christopher L. Bennett

The ongoing conflict between Spider-Man and his longtime outspoken nemesis, crusading newspaper publisher J. Jonah Jameson, reaches a whole new level when JJJ exploits several mysterious attacks on Manhattan island in his propaganda war against the web-slinger.

Marvel Classic Novels - Spider-Man: The Darkest Hours Omnibus