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This book combines fundamental concepts of biochemistry and the dental sciences to provide an authentic, coherent and comprehensive text for dental students. It describes in simple language the intricate pathophysiology of biomolecules in health and in diseases of dental and oral tissues. This book also describes the evolution of biochemistry in a chronological order, provides information about the fundamental chemical structure, classification and biological significance of biomolecules, vitamins and hormones, enriched with flow charts and diagrams for easy understanding and quick reference. It includes chapters on nucleic acids, nutrition and serum enzymes and organ function tests, and offers an innovative approach to familiarize dental students with the biochemical composition of enamel, dentine, cementum and saliva, explaining the biochemical basis of dental caries, periodontal diseases, role of fluorides in caries prophylaxis, fluoride toxicity, and the role of amino acids as anti-hypersensitive agents.

Comprehensive Biochemistry for Dentistry: Textbook for Dental Students

Module 1_Cellular Biochemistry.- Chapter 1. Cell and organelles.- Chapter 1.1.     Structure and Functions of cellular organelles.- Module 2_Structural Biochemistry: Chemistry and functions of Bio-macromolecules. - Chapter 2.1. Proteins and Amino acids.- Chapter 2.1.1. Organization of proteins.- Chapter 2.1.2. Plasma Proteins.- Chapter 2.1.3. Haemoglobin.- Chapter 2.1.4. Applied biochemistry - Implication of proteins in scurvy.- Chapter 2.2. Carbohydrates.- Chapter 2.2.1. Classification. - Chapter 2.2.2. Physiologically important Monosaccharides, Disaccharides, and Polysaccharides. - Chapter 2.2.3. Properties of Monosaccharides.- Chapter 2.2.4. Implication of Proteoglycans in Periodontitis.- Chapter 2.3. Lipids.- Chapter 2.3.1. Classification.- Phospholipids.- Chapter 2.3.2. Glycolipids.- Chapter 2.3.3. Cholesterol. - Chapter 2.3.4. Bile salts,  Micelle,  Bimolecular leaflet.- Chapter 2.3.5. Applied biochemistry - Dietary Omega - 3 fatty acid and dental diseases.- Chapter 2.4. Nucleic acids.- Chapter 2.4.1.Chemistry and metabolism of nucleotides.- Chapter 2.4.2. Structure of DNA.- Chapter 2.4.3. Types and Structure of RNAs.- Chapter 2.4.4.  DNA Replication.- Chapter 2.4.5. Transcription.- Chapter 2.4.6. Translation.- Chapter 2.4.7. Metabolism of Purines and Pyrimidines.- Chapter 2.4.8. Introduction to cancer and oncogene.-Chapter 2.5. Enzymes.- Chapter 2.5.1. Classification of enzymes.- Chapter 2.5.2. Enzyme Specificity.- Chapter 2.5.3. Factors affecting enzyme action.- Chapter 2.5.4.Type of enzyme inhibitions.- Chapter 2.5.5.Applied biochemistry - Important enzymes in dental diseases.- Chapter 2.6. Hormones.- Chapter 2.6.1.Types of hormones.- Chapter 2.6.2. Mechanism of action of hormones.- Chapter 2.6.3. Introduction, metabolic functions, clinical relevance of pituitary hormones, steroid hormones, thyroid hormones, Insulin and glucagon.- Chapter 2.6.4. Applied biochemistry-Role of Estrogen and Progesterone in inflammatory gingivitis. Chapter 2.7. Vitamins.- Chapter 2.7.1. Classification.- Chapter 2.7.2. Chemistry, Functions and deficiency symptoms of fat soluble and water soluble vitamins.- Chapter 2.7.4. Biosynthesis of Calcitriol and its functions.- Chapter 2.7.5. Applied biochemistry.- Module 3_Metabolism of Bio-macromolecules and Minerals.- Chapter 3.1. Metabolism of proteins.- Chapter 3.1.1. Digestion and absorption of Proteins.- Chapter 3.2. Metabolism of carbohydrates.- Chapter 3.2.1. Digestion and absorption of carbohydrates.- Chapter 3.3. Metabolism of lipids.- Chapter 3.3.1. Digestion and absorption of lipids.- Chapter 3.3.2. Clinical disorders.- Chapter 3.4. Metabolism of minerals.- Chapter 3.4.1. Applied biochemistry.- Chapter 3.5. Biological oxidation.- Chapter 3.5.1.- Introduction.- Chapter 3.5.2. Structure and function of Electron transport chain.- Chapter 3.5.3. Inhibitors of ETC.- Chapter 3.5.4. Applied biochemistry.- Module 4._Medical Biochemistry.- Chapter 4.1. Acid Base Balance.- Chapter 4.2. Nutrition.- Chapter 4.3. Diagnostic value of enzymes.- Chapter 4.4. Diagnostic value of enzymes.- Chapter 4.5. Clinical disorders.- Chapter 4.6. Liver and Gastric function tests.- Chapter 4.7. Renal function tests.- Module 5_Immunochemistry.- Chapter 5.1. Immunoglobulins.- Module 6_Dental Biochemistry.- Chapter 6.1. Chemistry of enamel, dentin and cementum.- Chapter 6.2. Chemical composition of saliva.- Chapter 6.3. Salivary proteins in health and disease.- Chapter 6.4. Chemistry of periodontal ligaments.- Chapter 6.5. Biochemical basis of Dental caries.- Chapter 6.6. Implication of fluorides.- Chapter 6.7. Role of Proteoglycans in dental plaque formation.- Chapter 6.8. Proteoglycans and cariogenic pathogens.