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The HDL Handbook: Biological Functions to Clinical Implications brings laboratory research in HDL from bench to bedside in this needed resource for researchers and clinicians studying cholesterol, lipids, epidemiology, biochemistry, molecular medicine, and pathophysiology of cardiovascular diseases. In addition, researchers and clinicians working with an aging population, corporate researchers, post-doctorates; medical students and graduate students will find this publication useful because the scope of coverage includes basic science, genetics, epidemiology, and treatment of HDL cholesterol as well as potential targets to modify HDL cholesterol.

Comprehensive coverage of basic science, genetics, epidemiology and treatment

Reputable content on latest advances in HDL cholesterol research

Inclusive, worldwide content with country specific information

In depth discussion of potential targets to modify HDL

The HDL Handbook: Biological Functions and Clinical Implications

Introduction

Role of phospholipid transfer protein (PLTP) in HDL remodelling and Atherosclerosis

The role of CETP in HDL metabolism

The physiological role of CETP in HDL molecule metabolism

HDL and reverse cholesterol transport: Physiological modulation

Serum Paraoxonase PON1 and its interactions with HDL: Relationship between PON1 and oxidative stress

Paraoxonase PON1 and its interaction with HDL: Molecular structures of PON1 and HDL

Apoliopoprotein A-I mutations

The Scavenger Receptor Class B Type I: An HDL Receptor Involved in Lipid Transport and HDL Dependent Signaling

HDL and its mimetic peptides: Novel therapeutic strategies for the treatment of inflammatory vascular disease

Sterol efflux by ABCA1 and ABCG1

Possible roles of oxidized HDL: Structural change of HDL particle by oxidative modification and its contribution to vascular diseases

Pre?1-HDL: Conversion to and from spherical ?-migrating HDL in human plasma

Determination of circulating native and denaturated HDL concentrations and its clinical implications