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Reproductive Immunology: Basic Concepts gives a holistic insight into the understanding of the complex interactions between the maternal immune system and the fetal/placental unit necessary for the success of pregnancy. This interaction is critical for the support of the human fetal semiallograft and the protection against infections. The book covers various topics such as B cells, macrophages, T cells, discussion on fetal signals and their impact on maternal reproductive cells such as endometrial cells, mast cells, and the role of fetal Hofbauer cells, the immune regulatory role of glucorticoids, and many other novel topics within the field of reproductive immunology.

Edited and written by experts in the field, this book introduces the up-to-date knowledge of the role of the immune system during pregnancy and provides the necessary background to understand pregnancy complications associated with alterations in the functioning of the immune system. The book provides a complete discussion on the immunological aspects of pregnancy and serves as a great tool for research scientists, students, reproductive immunologists and OBGYNs.

Reproductive Immunology: Basic Concepts

The role of the immune system during pregnancy: General concepts

Presentation and recognition of placental, fetal, and pathogen-derived antigens in human pregnancy

Uterine macrophages: Essential roles for a successful human pregnancy

Natural killer cells in reproduction: Before, during and after pregnancy

To B (e) born: New concepts concerning B cells throughout pregnancy

Neutrophils: Diverse functions in the endometrium of cycling women and during pregnancy

Regulatory T cells: Master regulators for the success of pregnancy

Immunology of the decidua

Mechanism of glucocorticoid action in immunology-Basic concepts

Endocrine control of mucosal immunity in the human female reproductive tract: Bridging implantation with pathogen protection

The nature of the immune response in microbial-associated and sterile intraamniotic inflammation

Autoimmunity, regulatory T cells, and pregnancy: Maintaining the balance

Mucosal immunology of the female reproductive tract and its regulation by female sex hormones

Toll-like receptors and NOD-like receptors at the implantation site

Hofbauer cells and placental viral infection

Gamma/delta T cells in pregnancy

Placental regulation of immune functions

TAM receptors in pregnancy

The epigenetic regulation of the immune system during pregnancy

Interactions between the epithelial barrier and the microbiota in the reproductive tract