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Clinical Chemistry considers what happens to the body's chemistry when affected by disease. Each chapter covers the relevant basic science and effectively applies this to clinical practice. It includes discussion on diagnostic techniques and patient management and makes regular use of case histories to emphasise clinical relevance, summarise chapter key points and to provide a useful starting point for examination revision.

The clear and engaging writing style appreciated by generations of readers has been retained in this new (eighth) edition, while the content has been thoroughly updated throughout. The approach and scope of this trusted text makes it ideal for integrated medical curricula for medical training and for students and practitioners of clinical and biomedical science. The complementary online version of the book, including additional self-assessment material, completes this superb learning package.

• Comes with complete, downloadable eBook on Student Consult
• Additional self-assessment materials - interactive clinical cases and two tier level MCQs ('standard' and 'advanced')
• New introductory chapter on basic biochemistry - including solutions, solutes, ionisation, pH, buffers, amino acids, peptides and proteins, enzyme activity, including kinetic properties, DNA structure
• 'Light bulb' sections give practical advice and clarify difficult concepts or potential pitfalls
• Updated references to core guidelines (UK and international) reflect latest best practice

Clinical Chemistry

1. An Introduction to Biochemistry and Cell Biology

2. Biochemical Investigations in Clinical Medicine

3. Water, Sodium and Potassium

4. Hydrogen Ion Homoeostasis and Blood Gases

5. The Kidneys

6. The Liver

7. The Gastrointestinal Tract

8. Clinical Nutrition

9. The Hypothalamus and the Pituitary Gland

10. The Adrenal Glands

11. The Thyroid Gland

12. The Gonads

13. Disorders of Carbohydrate Metabolism

14. Calcium, Phosphate and Magnesium

15. Bones and Joints

16. Plasma Proteins and Enzymes

17 Lipids, Lipoproteins and Cardiovascular Disease

18. Muscles, Nerves and Psychiatric Disorders

19. Inherited Metabolic Diseases

20. Disorders of Haemoproteins, Porphyrins and Iron

21. Metabolic Aspects of Malignant Disease

22. Therapeutic Drug Monitoring and Chemical Aspects of Toxicology

23. Clinical Chemistry at the Extremes of Age