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Bone Marrow Pathology has been extensively revised to reflect the significant advances which have occurred in the application of cytogenetics and in particular, molecular genetics in the diagnosis, classification and understanding of haematological disorders. This comprehensive book not only provides information on all common disease entities, but also covers rare disorders in which bone marrow examination is useful. It is designed as a practical resource with "problems and pitfalls" highlighted throughout to aid laboratory diagnosis.

Bone Marrow Pathology Fifth Edition

Preface to the fifth edition vi





Acknowledgements vii





Abbreviations viii





1 The normal bone marrow 1





2 Special techniques applicable to bone marrow diagnosis 61





3 Infection and reactive changes 109





4 Acute myeloid leukaemia mixed phenotype acute leukaemia the myelodysplastic syndromes and histiocytic neoplasms 185





5 Myeloproliferative and myelodysplastic/myeloproliferative neoplasms and related conditions 267





6 Lymphoproliferative disorders 346





7 Plasma cell neoplasms 487





8 Disorders of erythropoiesis granulopoiesis and thrombopoiesis 537





9 Miscellaneous disorders 585





10 Metastatic and non?haemopoietic tumours 645





11 Diseases of bone 685





Appendix 699





Index 709