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Computational Methods for Reproductive and Developmental Toxicology

Computational Methods for Reproductive and Developmental Toxicology

Autorzy
Wydawnictwo Taylor & Francis Inc
Data wydania 08/12/2015
Liczba stron 330
Forma publikacji książka w twardej oprawie
Poziom zaawansowania Dla profesjonalistów, specjalistów i badaczy naukowych
Język angielski
ISBN 9781439861073
Kategorie Toksykologia (nie medyczna)
876.75 PLN (z VAT)
$197.22 / €187.97 / £163.18 /
Produkt na zamówienie
Dostawa 5-6 tygodni
Ilość
Do schowka

Opis książki

Building from the perspective of reproductive and developmental biology, Computational Methods for Reproductive and Developmental Toxicology provides a timely and comprehensive overview of approaches in reproductive and developmental toxicology.


The book, which is part of the QSAR in Environmental and Health Sciences series, is divided into three broad sections. The first provides a review of methods and approaches to meet the need for safety assessments in product development and regulatory approaches for environmental chemicals. The next one reviews the biological processes and endpoints involved in reproduction and development.


The final and largest section summarizes protocols for evaluating biological processes and endpoints within reproduction and development. It also discusses informatics resources and computational methods.


The book takes a cross-disciplinary approach bringing together developmental, reproductive and systems biology, chemistry, toxicology, pharmacology, biostatistics, information sciences, bioinformatics, and computational approaches. This valuable resource provides those in the field with the necessary knowledge to evaluate both classic and recent approaches to characterize toxicity.

Computational Methods for Reproductive and Developmental Toxicology

Spis treści

INTRODUCTION



Introduction

Donald R. Mattison



Visions and Advancements for Meeting the Needs of Safety Assessment of Pharmaceutical and Industrial Chemicals

Karen A. Augustine-Rauch



REACH and Environmental Chemicals

Olivier Taboureau, Karine Audouze, and Soren Brunak



REPRODUCTION AND DEVELOPMENT: BIOLOGICAL PROCESSES AND ENDPOINTS



Female Reproductive Physiology

Mariangela Maluf and Paulo Marcelo Perin



Maternal Recognition of Pregnancy

Paulo Marcelo Perin and Mariangela Maluf



Early Embryo Development and Bipotential Gonad Formation

Paulo Marcelo Perin and Mariangela Maluf



Assessing the Reproductive Health of Men with Occupational Exposures

Steven M. Schrader, Susan Reutman, and Katherine L. Marlow



REPRODUCTION AND DEVELOPMENT: BIOLOGICAL AND COMPUTATIONAL METHODS



Animal Study Protocols and Alternative Assays for the Assessment of Reproductive and Developmental Toxicity

Aldert H. Piersma



US National Library of Medicine Resources for Computational Toxicology

Pertti J. Hakkinen



Modeling Endocrine Regulation of the Menstrual Cycle Using Delay Differential Equations

Leona A. Harris and James F. Selgrade



Molecular Structural Characteristics That Influence Partitioning of Xenobiotics into Human Breast Milk

Snezana Agatonovic-Kustrin and David W. Morton



Approaches for Pediatric Developmental Drug-Induced Liver Injury

William F. Salminen and Xi Yang



Adverse Outcome Pathways for Developmental Toxicity

Damiano Portinari and Philip N. Judson

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