This book provides a broad overview of the respiratory manifestations associated with Primary Immune deficiencies (PID) congenital genetic defects such as infections, chronic inflammation, autoimmunity, lymphoproliferation, allergic manifestations and rare forms of cancer. Since the most common site of involvement in PID is the lung, the pulmonologists (pediatrics or adult), Internists and General Practitioners may be among the first to recognize the pattern of pulmonary disorders, leading to diagnosis of PID. Pulmonary complications present a significant cause of morbidity and also mortality among patients suffering from different forms of PID. With the prevalence of lung infections and disease so high in PID patients, respiratory professionals will find this book to be an essential resource for diagnosing, managing and referring PID related pulmonary disorders in clinical practice.
Pulmonary Manifestations of Primary Immunodeficiency Diseases
1- General considerations.
2- Respiratory Manifestations of Combined T- and B-Cell Immunodeficiencies.
3- Respiratory Manifestations of Predominantly Antibody Deficiencies.
4- Respiratory Manifestations of Congenital Defects of Phagocytes.
5- Respiratory Manifestations of Genetic Disorders of Immune Regulation.
6- Respiratory Manifestations of Defects in Innate Immunity.
7- Respiratory manifestations of Autoinflammatory Disorders.
8- Respiratory manifestations of Complement Deficiencies.
9- Respiratory manifestations of Other Well-Defined Immunodeficiencies.
10- Treatment of Respiratory Manifestations in PIDs.