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This book is a comprehensive guide to our current understanding of idiopathic pulmonary fibrosis (IPF), its disease pathogenesis, genetic underpinnings, diagnosis, and management. Since the first edition, many new developments have occurred in the understanding and management of this serious disease, revising our understanding of how it presents, manifests, and reacts to certain treatments. This second edition is fully updated with six new chapters by our team of international, expert authors. New topics include: classification of interstitial lung disease, pulmonary function tests in IPF, biomarkers, clinical phenotypes, mimics, and a discussion of clinical trials. Each chapter additionally includes a brief summary of ongoing research and potential future directions. Idiopathic Pulmonary Fibrosis: A Comprehensive Clinical Guide , Second Edition is an invaluable resource for clinicians who desire a deeper understanding of IPF in order to better help their patients.

Idiopathic Pulmonary Fibrosis: A Comprehensive Clinical Guide

1.       Classification and Nomenclature of Interstitial Lung Disease

2.       Epidemiology and Natural History of IPF

3.       Histopathology of IPF and Related Disorders

4.       Imaging of IPF

5.       Pulmonary Function Tests in Idiopathic Pulmonary Fibrosis

6.       The Role of Immunity & Inflammation in IPF Pathogenesis

7.       Mechanisms of Fibrosis in IPF

8.       The Genetics of Pulmonary Fibrosis

9.       Genomics and Epigenetics of Pulmonary Fibrosis

10.   Biomarkers and IPF

11.   Clinical Phenotypes and Co-morbidities in IPF

12.   The Keys to Making a Confident Diagnosis of IPF

13.   Pharmacologic Treatment of IPF

14.   Mimics of IPF

15.   Gastroesophageal Reflux and IPF

16.   The Role of Pulmonary Rehabilitation and Oxygen Therapy

17.   Acute Exacerbations of IPF

18.   Lung Transplantation for IPF

19.   Clinical Trials in IPF: What Are the Best Endpoints?

20. Future Directions for IPF Research