Książki

The first handbook on this emerging field provides a comprehensive overview of transition metal-catalyzed coupling reactions in the presence of an oxidant. Following an introduction to the general concept and mechanism of this reaction class, the team of authors presents chapters on C-C cross-coupling reactions using organometallic partners, C-Heteroatom bond forming reactions via oxidative couplings, and C-H couplings via C-H activation. The text also covers such groundbreaking topics as recent achievements in the fields of C-C and C-X bond formation reactions as well as C-H activation involving oxidative couplings.With its novel and concise approach towards important building blocks in organic chemistry and its focus on synthetic applications, this handbook is of great interest to all synthetic chemists in academia and industry alike.

Oxidative Cross-Coupling Reactions

1. Introduction1.1 What's oxidative coupling?1.2 Why oxidative coupling?1.3 How does oxidative coupling work?1.4 Development and outlook2. Organometals as Nucleophiles 2.1 Classification and applications of organometallic reagents2.2 Csp-M and Csp-M as nucleophiles2.3 Csp-M and Csp2-M as nucleophiles2.4 Csp-M and Csp3-M as nucleophiles2.5 Csp2-M and Csp2-M as nucleophiles2.6 Csp2-M and Csp3-M as nucleophiles2.7 Csp3-M and Csp3-M as nucleophiles3. Oxidative Couplings involving the Cleavage of C-H Bonds 3.1 Theoretical understanding and methods in C-H bond activation3.2 Oxidative coupling between organometals and hydrocarbons3.3 Oxidative coupling between two hydrocarbons4. Bonding including Heteroatoms via Oxidative Coupling4.1 Oxidative C-O bond formation4.2 Oxidative C-N bond formation4.3 Bonding between carbon and other heteroatoms4.4 Bonding between two heteroatoms5. Oxidative Radical Couplings 5.1 Mechanistic studies5.2 Radical couplings5.3 Application of radical oxidative couplings in polymerizations