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Thermophiles and hyperthermophiles exhibit great biotechnological potential, as they can be utilized in processes which require higher temperatures. This book comprehensively deals with all the aspects of thermophiles, starting from the source of these organisms to their latest applications. In addition it presents a compilation of all compounds produced by various thermophilic microorganisms.  Due to their application in everyday life, the demands of enzymes that can work at higher temperature have been increasing. In order to keep pace with the increasing demand the industries have to search novel thermophiles producing their product of interest. Hence, this book will be of value for industries working on various biochemical products produced by these thermophiles as well as for scientists and research scholars working on microbiology and products derived from microorganisms. 

Thermophiles for Biotech Industry: A Bioprocess Technology Perspective

1: Introduction

1.1.Diversity of microorganisms.

1.2.Psychrophilic microorganisms and their habitat with examples.

1.3.Implications of Mesophilic microorganisms.

1.4.Habitat and diversity of Thermophilic microorganisms.

1.5.Hyperthermophilic microrganisms: challenges to the living world.

1.6.Biotechnology and bioprocess engineering of thermophiles

2: Thermophilic enzymes or heat stable enzymes: biochemical properties and commercial applications.

2.1.Oxidoreductases enzyme production from Thermophilic hosts.

2.2.

Thermophiles and their hot environment for Transferases production.

2.3.Hydrolytic enzymes and their thermophilic microbial sources.

2.4.Lyases from thermophiles and their applications.

2.5.Biotechnological potential of Isomerases from thermophilic microorganisms.

2.6.Thermophiles for the production of Ligases, molecular glue of biotechnology

2.7.

Recombinant enzyme production in thermophilic hosts

2.8.Enzyme kinetics

2.9.Immobilization of thermophilic enzymes

3: Thermophilic amino acids and proteins: current research and applications

3.1. Thermal stability of proteins

3.2. Factors affecting for thermal stability of proteins

3.3. Phenomena of protein folding system in Thermophiles

3.4. Significance of thermophilic proteins at Industrial level

3.5. Molecular mechanism of thermostable proteins from thermophiles

3.6. Thermophilic amino acids: building blocks of thermophilic proteins

3.7. Bioprocess considerations for thermophilic amino acids and

proteins

4: Organic compounds by thermophiles

4.1. Organic Acids from thermophilic microorganisms: Butyric acid, citric acid, lactic acid, acetic acid, 2,3-Butanediol

4.2. Production of Antimicrobial agents from thermophilic microbial sources:

4.3. Thermophilic microbial sources for the production of Alcohols: Bio ethanol

4.4. Growth kinetics during batch and continuous mode of operation

5: Other compounds and products from thermophiles

5.1. Lipopeptides by thermophiles: Biosurfactant

5.2. Glycolipids by thermophiles : Glycopilid, Rhamnolipid

5.3. Fatty acids and Natural Lipids from The thermophiles

5.4. Bio emulsifiers production from the thermophiles

5.5. Kinetic studies and bioprocess considerations in secondary metabolites

6: Applications of thermophilic microorganisms

6.1. Thermophiles as key players in environmental bioremediation

6.2. Role of thermophiles for the production of Biofuels

6.3. Importance of thermophiles in bio refinery

6.4. Significance of thermophiles in detergent industries

6.5. Potential of t

hermophiles in beverage industries

6.6. Modeling and optimization studies of bioprocesses

7. Problems and challenges while handling thermophiles

   

7.1. Handling and culturing of thermophiles

7.2. Maintenance and storage thermophiles at high temperature

7.3. Contamination of bio processes due to thermophiles

8. Conclusions