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Voet's Principles of Biochemistry, Global Edition addresses the enormous advances in biochemistry, particularly in the areas of structural biology and bioinformatics. It provides a solid biochemical foundation that is rooted in chemistry to prepare students for the scientific challenges of the future. New information related to advances in biochemistry and experimental approaches for studying complex systems are introduced. Notes on a variety of human diseases and pharmacological effectors have been expanded to reflect recent research findings. While continuing in its tradition of presenting complete and balanced coverage, this Global Edition includes new pedagogy and enhanced visuals that provide a clear pathway for student learning.

Voet's Principles of Biochemistry, 5th Edition Glo bal Edition

PART I INTRODUCTION





1 Life, Cell and Thermodynamics 1





2 Physical and Chemical Properties of Water 23





PART II BIOMOLECULES





3 Overview of DNA Structure, Function, and Engineering 42





4 Amino Acids 80





5 Polypeptide Analysis, Sequencing and Evolution 97





6 Proteins: Structure and Folding 131





7 Physiological Activities of Proteins 180





8 Saccharide Chemistry 221





9 Lipids, Bilayer and Membranes 245





10 Passive and Active Transport 293





PART III ENZYMES





11 Mechanisms of Enzyme Action 322





12 Properties of Enzymes 361





13 Hormones and Signal Transduction 402





PART IV METABOLISM





14 Bioenergetics 442





15 Glycolysis and the Pentose Phosphate Pathway 478





16 Additional Pathways in Carbohydrate Metabolism 523





17 The Citric Acid Cycle 558





18 Mitochondrial ATP Synthesis 588





19 Photosynthesis: Can be found at www.wiley.com/college/voet





20 Synthesis and Degradation of lipids 664





21 Synthesis and Degradation of Amino Acids 718





22 Regulation of Fuel Metabolism 773





PART V GENE EXPRESSION AND REPLICATION





23 Nucleotide Synthesis and Degradation 802





24 DNA structure and Interactions with Proteins 831





25 DNA Synthesis and Repair 879





26 RNA Metabolism 938





27 The Genetic Code and Translation 982





28 Gene Expression in Prokaryotes and Eukaryotes 1033





Solutions: Can be found at www.wiley.com/college/voet





Glossary G-1





Index I-1