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After thirty five years, Mandell, Douglas, and Bennett s Principles and Practice of Infectious Diseases, 8th Edition is still the reference of choice for comprehensive, global guidance on diagnosing and treating the most challenging infectious diseases. Drs. John E. Bennett and Raphael Dolin along with new editorial team member Dr. Martin Blaser have meticulously updated this latest edition to save you time and to ensure you have the latest clinical and scientific knowledge at your fingertips. With new chapters, expanded and updated coverage, increased worldwide perspectives, and many new contributors, Mandell, Douglas, and Bennett s Principles and Practice of Infectious Diseases, 8th Edition helps you identify and treat whatever infectious disease you see.

"I highly recommend Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, together with the included ExpertConsult, the on-line version of the book that is a searchable source and is available to a variety of platforms. It is updated twice each year and is an excellent solution for health-care professionals to keep informed of the latest knowledge" Reviewed by Graefes Arch Clin Exp Ophthalmol, March 2015

"..what an in depth textbook should be, a superb and vast, yet highly readable review of its topic." Reviewed by glycosmedia.com, Mar 2015

"Principles and Practice of Infectious Diseases has many features and formats that make it a comprehensive, current, and clear source of information" Reviewed by Graefes Arch Clin Exp Ophthalmol, Feb 2015

Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, 2 Vols.: Expert Consult Premium Edition - Enhanced Online Features and Print

Part I Basic Principles in the Diagnosis and Management of Infectious Diseases

Section A. Microbial Pathogenesis

1. A Molecular Perspective of Microbial Pathogenicity

2. Microbiome of Local Sites and their Unique Biology

3. Prebiotics, Probiotics and Synbiotics

Section B. Host Defense Mechanisms

Including

5. Adaptive Immunity: Antibodies and Immunodeficiencies

6. Mucosal Immunity

7. Granulocytic Phagocytes and Deficiency States

8. Complement and Deficiencies

9. Human Genetics and Infection

10. Nutrition, Immunity, and Infection

11. Evaluation of the Patient with Suspected Immunodeficiency and Other Host Defense Defects

Section C. Epidemiology of Infectious Disease

12. Epidemiologic Principles

13. Emerging and Reemerging Infectious Disease Threat

14. Bioterrorism: An Overview

Section D. Clinical Microbiology

15. The Clinician and the Microbiology Laboratory

Section E. Anti-Infective Therapy

16. Principles of Anti-infective Therapy

17. Molecular Mechanisms of Antibiotic Resistance in Bacteria

18. Pharmacokinetics and Pharmacodynamics of Anti-infective Agents

19. Penicillins

20. Cephalosporins

21. Other ß-Lactam Antibiotics

22. Antibiotic Allergy

23. Fusidic Acid

24. Aminoglycosides

25. Tetracyclines and Chloramphenicol

26. Rifamycins

27. Metronidazole

28. Macrolides, Clindamycin, and Ketolides

29. Glycopeptides (Vancomycin and Teicoplanin), Streptogramins (Quinupristin-Dalfopristin), and Lipopeptides (Daptomycin)

30. Polymyxins (Polymyxin B and Colistin)

31. Oxazolidinones

32. Sulfonamides and Trimethoprim

33. Quinolones

34. Unique Antibacterial Agents

35. Urinary Tract Agents: Nitrofurantoin and Methenamine

36. Topical Antibacterials

37. Antimycobacterial Agents

38. Drugs Active Against Fungi, Pneumocystis and Microsporidia

39. Drugs for Malaria

40. Drugs for Parasites Other Than Malaria

41. Drugs for Helminths

42. Antiviral Drugs General Principles

43. Antivirals Against Influenza and Other Respiratory Viruses

44. Antivirals Against Herpes Viruses

45. Antivirals Against Hepatitis Viruses

46. Other Antiviral Drugs

47. Immunomodulators

48. Hyperbaric Oxygen

49. Complementary and Alternative Medicines for Infectious Diseases

50. Antimicrobial Management: Cost and Resistance

51. Interpretation of Clinical Trials of Antimicrobial Agents

52. Outpatient Parenteral Antimicrobial Therapy

53. Tables of Antimicrobial Agent Pharmacology

Part II Major Clinical Syndromes

Section A. Fever

54. Temperature Regulation and the Pathogenesis of Fever

55. Fever of Unknown Origin

56. The Acutely Ill Patient with Fever and Rash

Section B. Upper Respiratory Tract Infections

57. The Common Cold

58. Pharyngitis

59. Acute Laryngitis

60. Acute Laryngotracheobronchitis (Croup)

61. Otitis Externa, Otitis Media, and Mastoiditis

62. Sinusitis

63. Epiglottitis

64. Infections of the Oral Cavity, Neck, and Head

Section C. Pleuropulmonary and Bronchial Infections

65. Acute Bronchitis

66. Chronic Obstructive Pulmonary Disease, Chronic Bronchitis, and Acute Exacerbations

67. Bronchiolitis

68. Acute Pneumonia

69. Empyema and Pleural Effusion

70. Lung Abscess

71. Chronic Pneumonia

72. Cystic Fibrosis

Section D. Urinary Tract Infections

73. Urinary Tract Infections

Section E. Sepsis

74. Sepsis, Severe Sepsis, and Septic Shock

Section F. Intra-Abdominal Infection

75. Peritonitis and Intraperitoneal Abscesses

76. Infections of the Liver and Biliary System

77. Pancreatic Infections

78. Splenic Abscess

79. Appendicitis

80. Diverticulitis and Typhlitis

Section G. Cardiovascular Infections

81. Endocarditis and Intravascular Infections

82. Prosthetic Valve Endocarditis

83. Infections of Non-Valvular Cardiovascular Devices

84. Prophylaxis of Infective Endocarditis

85. Myocarditis and P