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Reproductive Immunology

Reproductive Immunology

Publisher Academic Press
Year 01/02/2021
Edition First
Pages 460
Version paperback
Readership level Professional and scholarly
Language English
ISBN 9780128185087
Categories Immunology
$201.26 (with VAT)
739.94 PLN / €165.00 / £141.75
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Book description

Reproductive Immunology: Basic Concepts gives a holistic insight into the understanding of the complex interactions between the maternal immune system and the fetal/placental unit necessary for the success of pregnancy. This interaction is critical for the support of the human fetal semiallograft and the protection against infections. The book covers various topics such as B cells, macrophages, T cells, discussion on fetal signals and their impact on maternal reproductive cells such as endometrial cells, mast cells, and the role of fetal Hofbauer cells, the immune regulatory role of glucorticoids, and many other novel topics within the field of reproductive immunology. Edited and written by experts in the field, this book introduces the up-to-date knowledge of the role of the immune system during pregnancy and provides the necessary background to understand pregnancy complications associated with alterations in the functioning of the immune system. The book provides a complete discussion on the immunological aspects of pregnancy and serves as a great tool for research scientists, students, reproductive immunologists and OBGYNs.

Reproductive Immunology

Table of contents

The role of the immune system during pregnancy: General concepts
Presentation and recognition of placental, fetal, and pathogen-derived antigens in human pregnancy
Uterine macrophages: Essential roles for a successful human pregnancy
Natural killer cells in reproduction: Before, during and after pregnancy
To B (e) born: New concepts concerning B cells throughout pregnancy
Neutrophils: Diverse functions in the endometrium of cycling women and during pregnancy
Regulatory T cells: Master regulators for the success of pregnancy
Immunology of the decidua
Mechanism of glucocorticoid action in immunology-Basic concepts
Endocrine control of mucosal immunity in the human female reproductive tract: Bridging implantation with pathogen protection
The nature of the immune response in microbial-associated and sterile intraamniotic inflammation
Autoimmunity, regulatory T cells, and pregnancy: Maintaining the balance
Mucosal immunology of the female reproductive tract and its regulation by female sex hormones
Toll-like receptors and NOD-like receptors at the implantation site
Hofbauer cells and placental viral infection
Gamma/delta T cells in pregnancy
Placental regulation of immune functions
TAM receptors in pregnancy
The epigenetic regulation of the immune system during pregnancy
Interactions between the epithelial barrier and the microbiota in the reproductive tract

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