The latest release of Thieme's
knowledge base for synthetic methodology is adding more than 1,000
pages of new content, including the new reference library volume Flow
Chemistry in Organic Synthesis, edited by T. F. Jamison and G. Koch.
With Science of Synthesis 4.12
, synthetic chemists today are provided with up-to-date and complete information.
The latest addition to the reference library, Flow Chemistry in Organic
Synthesis, edited by T. F. Jamison and G. Koch, introduces the
principles and potential of flow chemistry for synthetic chemical
reactions. The authors of the volume - pioneers in both the practical
and conceptual aspects of flow chemistry - aim to make this potential
available to a wider audience. Far more than just the adaptation of
batch processes to flow systems, flow chemistry offers a paradigm shift
in chemical synthesis: continuous flow holds the power to access new
reaction types and chemistry space. The volume examines principles of
reactor design and automation, as well as separations and purifications
in flow systems. It discusses the application of flow to photochemistry,
electrochemistry, gaseous systems, using immobilised reagents and
catalysts, and in multistep processes. In addition to covering syntheses
of peptides, carbohydrates, and pharmaceuticals, the work includes
several chapters on the use of flow in an industrial context. Flow
Chemistry in Organic Synthesis comprises a total of approx. 590 pages.
Among the highlights of the latest Knowledge Update is the major
revision of the chapter on benzo[c]furans or isobenzofurans by H.
Kwiecień. While these compounds are highly reactive and can normally
only be isolated after trapping, for example by Diels-Alder reaction
with dienophiles, 1,3-diarylbenzo[c]furans and
1,3-dihydroisobenzofuran-1(3H)-ones (phthalides) are much more stable.
The new Knowledge Update volume comprises a total of approx. 500 printed
pages, representing up-to-date and reliable synthetic methods. SOS
Knowledge Updates are governed by clearly defined criteria for method
selection as well as established editorial processes. The Editorial
Board, in conjunction with the volume editors and authors, reviews the
whole field of synthetic organic chemistry as presented in SOS and
evaluate significant developments in synthetic methodology. With expert
evaluated content focusing on subjects of particular current interest,
the SOS Reference Library complements the SOS Knowledge Updates to make
SOS the complete information source for the modern synthetic chemist. Brought to you by Scope e-Knowledge Center,
a trusted global partner for digital content transformation solutions -
Abstracting & Indexing (A&I), Knowledge Modeling (Taxonomies,
Thesauri and Ontologies), and Metadata Enrichment & Entity