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Research on ionic liquids has drastically increased over the past two decades. Ionic liquids are now a topic of major interest for chemists - both academics and professionals - across the world.The chapters in this book, taken together, represent how the field of ionic liquids is progressing and evolving. Current research on finding various other applications of ionic liquids is an interdisciplinary endeavor that brings together various disciplines such as synthetic, organic, bioorganic, medicinal and biological chemistry, chemical biology, pharmacology, biochemistry, toxicology, materials sciences etc. The authors intend these communities in particular to draw great benefit from thisbook. The authors seek to encourage and stimulate ongoing and new interdisciplinary research activities on the development of novel applications of ionic liquids in the biomedical fields.

Ionic Liquid Applications: Pharmaceuticals, Therapeutics, and Biotechnology

From the contents:

Preface;
1. Ionic Liquids as Pharmaceutical Salts: A Historical Perspective;
Vineet Kumar and Sanjay V. Malhotra;
2. Ionic Liquids: New Opportunities for the Chemistry of Amino Acids, Peptides, and Pharmaceutical Compounds;
James Ternois, Laurent Ferron, Gérard Coquerel, Frédéric Guillen, and Jean-Christophe Plaquevent;
3. Enzymatic Membrane Reactor for Resolution of Ketoprofen in Ionic Liquids and Supercritical Carbon Dioxide Pedro Lozano, Teresa De Diego, Arturo Manjón, Miguel A. Abad, Michel Vaultier, and José L. Iborra;
4. Development of a Universal Method Based on Ionic Liquids for Determination of Enantiomeric Compositions of Pharmaceutical Products;
Chieu D. Tran;
5. New Method for Installation of the Imidazole Ring and Synthesis of Biologically Active Molecules with Ionic Liquid-Like Structures;
Yuichi Kobayashi, Yohei Kiyotsuka, Hukum P. Acharya, and Key Miyoshi;
6. Separation and Recovery of Penicillin in an Integrated System Containing Ionic Liquids;
Yangyang Jiang, Chen Guo, Hansong Xia, and Huizhou Liu;
7. Enzymatic Hydrolysis of Penicillin in an Integrated System Containing Ionic Liquids;
Yangyang Jiang, Chen Guo, Hansong Xia, and Huizhou Liu;
8. Antitumor Activity of Ionic Liquids on Human Tumor Cell Lines;
Vineet Kumar and Sanjay V. Malhotra;
9. Preparation of Ionic Liquid-Modified Inorganic Nanoparticles and Their Biomedical Application;
Asako Narita, Kensuke Naka, and Yoshiki Chujo;
10. Preparation of Biopolymer-Based Materials Using Ionic Liquids for the Biomedical Application;
Sang Hyun Lee, Minoru Miyauchi, Jonathan S. Dordick, and Robert J. Linhardt;
11. Toxicological Evaluation of Ionic Liquids;
Raquel F. M. Frade, Ana Matias, Luis C. Branco, Nuno M. T. Lourenço, Joao N. Rosa, Carlos A. M. Afonso, and Catarina M. M. Duarte;
12. Formation of Anhydrosugars from Polysaccharides in Ionic Liquids by Microwave Irradiation;
Hiroe Satoh, Momoko Hayashi, Toshifumi Satoh, Toyoji Kakuchi, Harumi Kaga, and Kenji Takahashi;
13. Chiral Pyrrolidine-Substituted Ionic Liquid-Mediated Activation of Enzyme;
Toshiyuki Itoh, Yoshikazu Abe, Takuya Hirakawa, Nagisa Okano, Shino Nakajima, Shuichi Hayase, Motoi Kawatsura, Tomoko Matsuda, and Kaoru Nakamura;
14. Deep Eutectic Solvents for Candida antarctica Lipase B-Catalyzed Reactions;
Johnathan T. Gorke, Friedrich Srienc, and Romas J. Kazlauskas;
15. Enzyme Catalysis in Ionic Liquids and Supercritical Carbon Dioxide;
Pedro Lozano, Teresa De Diego, Michel Vaultier, and José L. Iborra;
16. On the Merge of Fungal Activity with Ionic Liquids towards the Development of New Biotechnological Processes;
M. Petkovic, J. Ferguson, A. Bohn, J. R. Trindade, I. Martins, C. Leitao, M. B. Carvalho, C. Rodrigues, H. Garcia, R. Ferreira, K. R. Seddon, L. P. N. Rebelo, and C. Silva Pereira