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As the science and practice of haematology continues to advance at a considerable rate, Haematology Lecture Notes remains a comprehensive guide to this diverse subject, and provides support in understanding the pathogenesis and management of haematological disorders. Successfully integrating the physiological, pathological, and clinical aspects of haematology, this new edition includes new material on molecular and cellular diagnostics, expanded coverage on haemostasis, malignant haematology and transplant, and features self-assessment questions at the end of each chapter. Thoroughly revised and updated, Haematology Lecture Notes provides the core subject knowledge required by students and junior doctors to excel in this specialty.

Lecture Notes: Haematology

Preface, vii


About the companion website, ix


1 An introduction to haematopoiesis, 1


2 Anaemia: General principles, 11


3 Haemolytic anaemias, 27


4 Disorders of globin synthesis, 41


5 Conditions associated with white cell abnormalities, 55


6 Structure and function of lymphoid tissue, 65


7 Lymphomas: General principles, 71


8 Classification of lymphoma, 81


9 Neoplastic disorders of lymphoid cells, 85


10 Plasma cell myeloma and other paraproteinaemias, 97


11 Neoplastic disorders of myeloid cells, 105


12 Bone marrow transplantation, 117


13 Aplastic anaemia and pure red cell aplasia, 125


14 Haemostasis, abnormal bleeding and anticoagulant therapy, 131


15 Blood groups and blood transfusion, 151


16 Cellular and molecular investigations in haematology, 163


Index, 173 vi