The World Health Organization estimates that 25 percent of common cancers can be prevented through regular physical activity and weight control. Common cancers linked to overweight/obesity and a sedentary lifestyle include breast, colon, endometrium, pancreas, renal, esophageal, and several others. There are several plausible mechanisms linking lack of physical activity and increased adiposity to cancer risk, supported by results from animal experiments and human intervention studies.
Physical Activity, Dietary Calorie Restriction, and Cancer
Chapter 1: Introduction
Anne McTiernan, MD, PhD
Rachel Ballard-Barbash, MD, MPH
Linda Nebeling, PH.D., MPH, RD, FADA
Chapter 2: Epidemiology of overweight/obesity and cancer risk
Dr Andrew Renehan PhD FRCS
Chapter 3: Epidemiology of physical activity and cancer risk.
Becky Speck
Kathryn Schmitz, PhD
I-Min Lee, MD, ScD
Anne McTiernan, MD, PhD
Chapter 4: Dietary energy restriction, exercise, and mammary carcinogenesis
Henry Thompson, PhD
Chapter 5: Calorie restriction, exercise, and colon cancer prevention: a mechanistic perspective
Connie Rogers, PhD
Susan Perkins, PhD
Steve Hursting, PhD
Chapter 6: Mechanisms linking obesity to cancer risk in humans
Ikuyo Imayama, MD, PhD, Caitlin Mason, PhD, Catherine Duggan, PhD
Chapter 7: Mechanisms underlying the effects of physical activity on cancer
Andrew Rundle, PhD
Chapter 8: Physical activity, weight control, and cancer prognosis
Kathryn Schmitz, PhD
Melinda L. Irwin, PhD, MPH