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Regulating with RNA in Bacteria and Archaea

Regulating with RNA in Bacteria and Archaea

Autorzy
Wydawnictwo American Society for Microbiology
Data wydania 01/11/2018
Wydanie Pierwsze
Liczba stron 576
Forma publikacji książka w twardej oprawie
Poziom zaawansowania Dla profesjonalistów, specjalistów i badaczy naukowych
Język angielski
ISBN 9781683670230
Kategorie Sprzęt medyczny i techniki, Mikrobiologia i wirusologia, Biochemia
665.84 PLN (z VAT)
$173.36 / €155.60 / £133.97 /
Produkt na zamówienie
Przesyłka w 3-4 tygodnie
Ilość
Do schowka

Opis książki

Revealing the many roles of RNA in regulating gene expression For decades after the discoveries of messenger RNA, transfer RNA, and ribosomal RNA, it was largely assumed that the role of RNA in the cell was limited to shuttling the genomic message, chaperoning amino acids, and toiling in the ribosomes. Eventually, hints that RNA molecules might have regulatory roles began to appear. With the advent of genomics and bioinformatics, it became evident that numerous other RNA forms exist and have specific functions, including small RNAs (sRNA), RNA thermometers, and riboswitches to regulate core metabolic pathways, bacterial pathogenesis, iron homeostasis, quorum sensing, and biofilm formation. All of these functions, and more, are presented in Regulating with RNA in Bacteria and Archaea, written by RNA biologists from around the globe. Divided into eight sections?RNases and Helicases, Cis-Acting RNAs, Cis Encoded Base Pairing RNAs, Trans-Encoded Base Pairing RNAs, Protein Titration and Scaffolding, General Considerations, Emerging Topics, and Resources?this book serves as an excellent resource for established RNA biologists and for the many scientists who are studying regulated cellular systems. It is no longer a fair assumption that gene expression regulation is the provenance of proteins only or that control is exerted primarily at the level of transcription. This book makes clear that regulatory RNAs are key partners along with proteins in controlling the complex interactions and pathways found within prokaryotes. Finally! One spectacular volume provides us all we need to educate ourselves in the fascinating world of regulatory RNAs in bacteria and archaea. From the genetics to the biochemistry to the mechanisms to the structures to the physiology to the networks to the challenges for the future--it's all here--laid out for us in exceptional form by the world's key experts. This volume is an eye-opening must read about one of microbiology's most exciting emerging fields. --Bonnie L. Bassler, Ph.D., HHMI Investigator, Squibb Professor and Chair of the Department of Molecular Biology, Princeton University

Regulating with RNA in Bacteria and Archaea

Spis treści

Contributors


Foreword


Preface


Acknowledgments


About the Editors


Section I: RNases and Helicases


1. RNase E and the High-Fidelity Orchestration of RNA Metabolism
Katarzyna J. Bandyra and Ben F. Luisi


2. Enzymes Involved in Posttranscriptional RNA Metabolism in Gram-Negative Bacteria
Bijoy K. Mohanty and Sidney R. Kushner


3. RNases and Helicases in Gram-Positive Bacteria
Sylvain Durand and Ciaran Condon


Section II: Cis-acting RNAs


4. RNA Thermometers in Bacterial Pathogens
Edmund Loh, Francesco Righetti, Hannes Eichner, Christian Twittenhoff, Franz Narberhaus


5. Small Molecule-Binding Riboswitches
Thea S. Lotz and Beatrix Suess


6. The T-Box Riboswitch: tRNA as an Effector to Modulate Gene Regulation
Kiel D. Kreuzer and Tina M. Henkin


7. rRNA Mimicry in RNA Regulation of Gene Expression
Michelle M. Meyer


8. Processive Antitermination
Jonathan R. Goodson and Wade C. Winkler


9. Genes within genes in bacterial genomes
Sezen Meydan, Nora Vazquez-Laslop, and Alexander S. Mankin


10. Leaderless mRNAs in the Spotlight: Ancient but Not Outdated!
Heather J. Beck and Isabella Moll


Section III: Cis-encoded base pairing RNAs


11. Type I Toxin-Antitoxin Systems: Regulating Toxin Expression via Shine-Dalgarno Sequence Sequestration and Small RNA Binding
Sara Masachis and Fabien Darfeuille


12. Widespread Antisense Transcription in Prokaryotes
Jens Georg and Wolfgang R. Hess


Section IV: Trans-encoded base pairing RNAs


13. Small Regulatory RNAs in the Enterobacterial Response to Envelope Damage and Oxidative Stress
Kathrin S. Froehlich and Susan Gottesman


14. Carbohydrate Utilization in Bacteria: Making the Most Out of Sugars with the Help of Small Regulatory RNAs
Svetlana Durica-Mitic, Yvonne Goepel, Boris Goerke


15. Small RNAs Involved in Regulation of Nitrogen Metabolism
Daniela Prasse and Ruth A. Schmitz


16. Bacterial Iron Homeostasis Regulation by sRNAs
Sylvia Chareyre and Pierre Mandin


17. Small-RNA-Based Regulation of Bacterial Quorum Sensing and Biofilm Formation
Sine Lo Svenningsen


18. Regulatory RNAs in Virulence and Host-Microbe Interactions
Alexander J. Westermann


Section V: Protein titration and scaffolding


19. Global Regulation by CsrA and Its sRNA Antagonists
Tony Romeo and Paul Babitzke


20. 6S RNA, a Global Regulator of Transcription
Karen M. Wassarman


21. Bacterial Y RNAs: Gates, Tethers, and tRNA Mimics
Soyeong Sim and Sandra L. Wolin


Section VI: General considerations


22. Proteins That Chaperone RNA Regulation
Sarah A. Woodson, Subrata Panja, and Andrew

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