Książki

This book looks at the mathematical foundations of the models currently in use. All existing books on bioinformatics are software-orientated and they concentrate on computer implementations of mathematical models of biology. This book is unique in the sense that it looks at the mathematical foundations of the models, which are crucial for correct interpretation of the outputs of the models.

Introduction to Mathematical Methods in Bioinformatics

Sequence Analysis.- Introduction: Biological Sequences.- Sequence Alignment.- Markov Chains and Hidden Markov Models.- Protein Folding.- Phylogenetic Reconstruction.- Mathematical Background for Sequence Analysis.- Elements of Probability Theory.- Significance of Sequence Alignment Scores.- Elements of Statistics.- Substitution Matrices.