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This book explores the latest developments in the field the acute phase protein (APP), C-reactive protein or CRP in different diseases, highlighting the structural and functional aspects of CRP in disease biology.

Divided into 5 sections, the book examines important topics such as the role of CRP in neurodegenerative, cardiac and parasitic diseases, as well as in cancer and inflammatory bowel disease, and the expression of CRP in pediatric respiratory diseases. In addition it discusses the clinical role of CRP in diagnostics and therapeutics, sepsis, ICU and ITU patients, and also as a primary marker for inflammation. Given its scope, this book will appeal to scholars in various fields of medicine and biology.

Clinical Significance of C-reactive Protein

A. Introduction
B. Structure and function of CRP1. Single nucleotide polymorphisms and CRP2. Structure of CRP, glycosylation, microheterogeneity
3. Serum proteins, acute phase response, inflammation

C. Clinical applications of CRP4. Clinical role of CRP in diagnostics and therapeutics5. Clinical role of glycosylated serum proteins
D. CRP in selected diseases6. CRP and autoimmune diseases and role in rheumatoid arthritis7. CRP and  pediatric diseases8. CRP and neurodegenerative disorders
9. CRP and tuberculosis10. CRP in sepsis, ICU and ITU patients
11. CRP and cardiac diseases12. CRP and Parasitic diseases13. CRP and respiratory diseases14. CRP and diabetes15. CRP and cancer