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The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. This work presents research covering the conceptual advances on aspects such as the characterization of virus structure, cellular receptors, mechanisms of virus entry, host and viral components of the RNA replicase.

Advances in Virus Research v59

Taxonomy of the virus family Flaviviridae

Structure and replication

Molecular Biology of the Flaviviruses

Flavivirus Structure and Membrane Fusion

Kunjin RNA replication and applications of Kunjin replicons

Antigenic structure of flavivirus Proteins

5' and 3' non-coding regions in flavivirus RNA

Manipulation of Cell Surface Macromolecules by Flaviviruses

Flavivirus evolution

Origins, Evolution and vecto/host cp-adaptations within the genus Flavivirus

Microevolution and virulence of dengue viruses