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The Pituitary, Fourth Edition, continues the tradition of a cogent blend of basic science and clinical medicine which has been the successful hallmark of prior editions. This comprehensive text is devoted to the pathogenesis, diagnosis, and treatment of pituitary disorders. The new edition has been extensively revised to reflect new knowledge derived from advances in molecular and cell biology, biochemistry, diagnostics, and therapeutics as they apply to the pituitary gland.

The wide spectrum of clinical disorders emanating from dysfunction of the master gland is described in detail by experts in the field. Fundamental mechanisms underlying disease pathogenesis are presented to provide the reader with an in-depth understanding of mechanisms subserving both normal and disordered pituitary hormone secretion and action.

This extensive body of knowledge is useful for students, trainees, physicians, and scientists who need to understand critical pituitary functions and how to care for patients with pituitary disorders. Chapters provide medical students, clinical and basic endocrinology trainees, endocrinologists, internists, pediatricians, gynecologists, and neurosurgeons with a comprehensive, yet integrated, text devoted to the science and art of pituitary medicine.

• Brings together pituitary experts from all areas of research and practice who take readers all the way from bench research, to genomic and proteomic analysis, clinical analysis, and new therapeutic approaches to pituitary disorders
• Saves researchers and clinicians time in quickly accessing the very latest details on a broad range of issues related to normal and diseased pituitary function
• Provides a common language for endocrinologists, neurosurgeons, OB/GYNs, and endocrine researchers to discuss how the pituitary gland and hormones affect each major organ system

The Pituitary

Section I: Hypothalamic-Pituitary Function 1. Pituitary Development 2. Hypothalamic Regulation of Anterior Pituitary Function 3. Adrenocorticotrophin 4. Growth Hormone 5. Prolactin 6. Thyroid-Stimulating Hormone 7. Gonadotrophin Hormones 8. The Posterior Pituitary

Section II: Hypothalamic-Pituitary Disorders 9. The Hypothalamus 10. Anterior Pituitary Failure 11. Pituitary Dysfunction in Systemic Disorders 12. Drugs and Pituitary Function 13. The Pituitary Gland in Pregnancy 14. Psychiatric Disease in Hypothalamic-Pituitary Disorders

Section III: Pituitary Tumors 15. Acromegaly 16. Prolactinoma 17. Cushing Disease 18. Thyrotrophin-Secreting Pituitary Tumors 19. Nonfunctioning and Gonadotrophin-Secreting Adenomas 20. Atypical Pituitary Adenomas 21. Genetics of Pituitary Tumor Syndromes 22. Nonpituitary Sellar Masses

Section IV: Pituitary Procedures 23. Pituitary Imaging 24. Pituitary Surgery