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The two-part, fifth edition of Advanced Organic Chemistry has been substantially revised and reorganized for greater clarity. The material has been updated to reflect advances in the field since the previous edition, especially in computational chemistry. Part B describes the most general and useful synthetic reactions, organized on the basis of reaction type. It can stand-alone; together, with Part A: Structure and Mechanisms, the two volumes provide a comprehensive foundation for the study in organic chemistry. Companion websites provide digital models for students and exercise solutions for instructors. From the reviews of the fifth edition:



"Advanced Organic Chemistry ... the well-known textbook for graduate students - has now appeared in a 5th edition. ... Carey & Sundberg will be interesting to all students who seek a detailed understanding of organic chemistry, and who wish to refresh and embellish their existing knowledge. On the strength of the scope and quality of the explanations, this pair of texts is recommended for use as the resource of first resort for specific research questions in one's later career." (www.organische-chemie.ch, January, 2008)

Advanced Organic Chemistry: Part B: Reaction and Synthesis

Alkylation of Enolates and Other Carbon Nucleophiles.- Reactions of Carbon Nucleophiles with Carbonyl Compounds.- Functional Group Interconversion by Substitution, Including Protection and Deprotection.- Electrophilic Additions to Carbon-Carbon Multiple Bonds.- Reduction of Carbon-Carbon Multiple Bonds, Carbonyl Groups, and Other Functional Groups.- Concerted Cycloadditions, Unimolecular Rearrangements, and Thermal Eliminations.- Organometallic Compounds of Group I and II Metals.- Reactions Involving Transition Metals.- Carbon-Carbon Bond-Forming Reactions of Compounds of Boron, Silicon, and Tin.- Reactions Involving Carbocations, Carbenes, and Radicals as Reactive Intermediates.- Aromatic Substitution Reactions.- Oxidations.- Multistep Syntheses.