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An informative handbook on the staging of cancer and the selection and evaluation of cancer treatment. ESMO Handbook on Treatment Evaluation in Cancer is an ideal resource for medical oncologists and those involved in screening and chemotherapy programs.





The text demonstrates how to judge various prognostic and predictive factors, how to determine the relevance of staging, and how to measure patient response for each cancer type.





Written by an international team of experts, this progressive text incorporates the fast-moving world of research into the field of cancer genetics and prevention.





Topics discussed include:







epidemiology
genetics of cancer
sporadic cancers
hereditary cancers
primary prevention of cancer
screening programmes for the general population
screening programmes for those at higher risk
the role of prevention
secondary prevention of cancer

Esmo Handbook on Treatment Evaluation in Cancer

Introduction

Pathology

Introduction

Aims in diagnosis and treatment

Clinical implications and use

Biomarkers in oncology

Introduction

Clinically useful tumor markers

"Omics"

Conclusions

Radiological imaging

Introduction

Plain X rays

Ultrasound

Computed tomography

Magnetic resonance imaging

Newer techniques

Nuclear medicine imaging

Introduction

Positron emission tomography

Staging procedures

Aim of staging procedures

Relevant staging procedures in daily clinical practice

Head and neck tumors

Small cell lung cancer

Non-small cell lung cancer

Esophageal cancer

Gastric cancer

Colorectal cancer

Breast cancer

Prostate cancer

Bladder cancer

Renal cell cancer

Endometrial cancer

Ovarian cancer

Malignant melanoma

Non-Hodgkin's lymphoma

Hodgkin's disease

Prognostic criteria

Introduction

Patient-related prognostic factors

Tumor-related prognostic factors

Conclusion

Predictive tumor markers

Introduction

Tumor markers: definition and types

Tumor markers: evaluation of their clinical utility

Tumor markers: methodological, statistical, and reporting considerations

Predictive tumor markers in routine use or in development

Conclusion

Factors determining anticancer treatment

Introduction

Disease-related factors

Patient-related factors

Treatment-related factors

Sociocultural factors

Conclusion

Treatment evaluation of activity: From global to personalized approach

Introduction

Evaluation of the treatment of solid tumors

Acute and subacute toxicities of medical anticancer treatment

Introduction

Tissue necrosis and phlebitis

Nausea and vomiting

Hypersensitivity reactions

Tumor lysis syndrome

Flu-like syndrome

Hematologic toxicity

Mucositis (stomatitis, diarrhea)

Hair loss

Skin toxicity

Pancreatitis

Liver toxicity

Constipation and ileus

Early-onset pulmonary toxicity

Metabolic complications

Late toxicity

Introduction

Methodological aspects

Second cancer

Cardiovascular disease

Endocrine effects

Other long-term effects

Conclusion

Acute and late effects in radiation oncology and surgery

Introduction

Radiotherapy

Surgery

Psychosocial effects of cancer and treatment

Introduction

Psychosocial consequences

Long-term survivorship

Vulnerable cancer patients

The role of the psychologist in oncology

The role of the oncologist

Psychological screening

Conclusion

Incapacity due to cancer and cancer therapy

Introduction

General weakness and fatigue

Cognitive and emotional impairment

Neuropathy

Gastrointestinal impairment

Bladder disorders

Sexual dysfunction

Conclusion

Reintegration into the workplace

Introduction

Guidelines for integration

Barriers for reintegration into the workplace

Requalification and job applications

Retirement

Conclusion

Quality of life issues

Introduction

HRQOL in clinical trials: design and its impact on clinical results

Using HRQOL measures in daily clinical practice: clinical impact

Conclusion

Conclusion