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Antiphospholipid syndrome is an autoimmune disease that causes abnormal blood clots. It is now recognized as a major cause of common conditions, including stroke, heart attack, miscarriage, epilepsy and memory loss and as such is gaining recognition in all branches of medicine, from obstetrics to cardiology, from psychiatry to orthopedics.

This book provides an overview of our current understanding of this major disease. It includes the latest information on the new pathogenetic mechanisms involved as well as clinical manifestations in both "the thrombotic" and "non-thrombotic" manifestations of this important disease. Immunologists, rheumatologists, obstetricians, hematologists, fellows, medical student and those working in internal medicine and general medicine. As well as medical/scientific management and pharmaceutical companies.

Antiphospholipid Syndrome in Systemic Autoimmune Disease

Classification and Epidemiology of the Antiphospholipid Syndrome;

Laboratory Heterogeneity of the Antiphospholipid Antibodies:

Pathogenesis of the Antiphospholipid Syndrome;

Immunogenetics of the Antiphospholipid Syndrome;

Systemic Manifestations of the Antiphospholipid Syndrome;

Obstetric Manifestations of the Antiphospholipid Syndrome;

Antiphospholipid Antibodies and Infections and Drugs;

Antiphospholipid Antibodies and Malignancies;

Antiphospholipid Antibodies and Vascular Disorders (Atheromatosis and Vasculitis);

Treatment of the Antiphospholipid Syndrome;

Difficult situations in the Antiphospholipid Syndrome;