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Now in a revised edition, Comparative Pharmacokinetics: Principles, Techniques, and Applications presents the principles and techniques of comparative and veterinary pharmacokinetics in a detailed yet practical manner.

Comparative Pharmacokinetics: Principles, Techniques and Applications

Preface.Chapter 1: Introduction.Chapter 2: Principles of Drug Movement in the Body.Chapter 3: Quantitative Structure Permeability Relationships (QSPeR).Chapter 4: Absorption.Chapter 5: Distribution.Chapter 6: Renal Elimination.Chapter 7: Hepatic Biotransformation and Biliary Excretion.Chapter 8: Compartmental Models.Chapter 9: Noncompartmental Models.Chapter 10: Nonlinear Models.Chapter 11: Physiological Models.Chapter 12: Dosage Regimens.Chapter 13: Simultaneous Pharmacokinetic-Pharmacodynamic Modeling.Chapter 14: Study Design and Data Analysis.Chapter 15: Design and Analysis of Bioequivalence Studies and FDA's in vitro/in vivo (IVIV).Chapter 16: Population Pharmacokinetic Models and the Bayesian Forecasting Applied to Clincal Pharmacokinetics.Chapter 17: Dosage Adjustments in Renal (and Hepatic) Disease.Chapter 18: Interspecies Extrapolations.Chapter 19: Tissue Residues and Withdrawal TimesAppendix