This book is for undergraduate students, graduate students and professionals in biology and other sciences who require a concise but comprehensive introduction to population genetics. Starting with the basic concepts of molecular genetics, it examines the principal methods by which DNA (or proteins) can be manipulated to reveal genetic polymorphisms in any population. Numerous practical examples are included, showing how the theoretical concepts are applied to actual data. To reinforce ideas, each chapter concludes with about 20 problems, arranged in order of difficulty.
A Primer of Population Genetics
PART 1: GENETIC VARIATION.- Genetic and Molecular Essentials.- Types of Polymorphisms.- Organization of Genetic Variation.- Inbreeding.- PART 2: THE CAUSES OF EVOLUTION.- Mutation.- Migration.- Natural Selection.- Random Genetic Drift.- PART 3: MOLECULAR POPULATION GENETICS.- Molecular Polymorphisms.- Patterns of Change in Nucleotide and Amino Acid Sequences.- Polymorphism and Divergence.- Molecular Phylogenetics.- Transposable Elements.- PART 4: THE GENETIC ARCHITECTURE OF COMPLEX TRAITS.- Types of Complex Traits .- Phenotypic Variation.- Genetics and Environment.- Artificial Selection.- Correlation between Relatives.- Quantitative Genetics of Natural Populations.- Complex Traits With Discrete Expression.- Quantitative Trait Loci (QTLs).- Literature Cited.- Index.