Unique in in its focus on eukaryotic molecular biology, this textbook provides a distillation of the essential concepts of molecular biology, supported by current examples, experimental evidence, and boxes that address related diseases, methods, and techniques. End-of-chapter analytical questions are well designed and will enable students to apply the information they learned in the chapter. A supplementary website include self-tests for students, resources for instructors, as well as figures and animations for classroom use.
Fundamental Molecular Biology
1. The Beginnings of Molecular Biology
2. The Structure of DNA
3. The Versatility of RNA
4. Protein Structure and Folding
5. Genome Organization and Evolution
6. DNA Replication and Telomere Maintenance
7. DNA Repair Pathways
8. Recombinant DNA Technology and Molecular Cloning
9. Tools for Analyzing Gene Expression
10. Transcription in Bacteria
11. Transcription in Eukaryotes
12. Epigenetic Mechanisms of Gene Regulation
13. RNA Processing and Posttranscriptional Gene Regulation
14. The Mechanism of Translation
15. Genetically Modified Organisms
16. Genome Analysis
17. Medical Molecular Biology