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When the projected volumes of the Handbook are completed, most of our current knowledge of the biochemistry of nervous systems will have been touched upon. A number of the chapters will have dealt with the correlations of the biochemical findings with morphological and physio logical parameters as well. Considering the abysmal lack of such attempts, even in the recent past, this is a sign of great progress. If the reader's eventual goal is to derive the "laws" that relate various aspects of animal and human behavior to underlying physiological and biochemical function, these admirable volumes will help him to establish a firm biochemical base from which to operate. It is certain that the future approaches to the various problems of the information-processing functions of the nervous system will require an integrated understanding of the essence of all of the scientific disciplines which are grouped under the general name of neuro biology. The rich feast of information offered up in this Handbook will enable those in the non-chemical disciplines to pick and choose those areas of chemical information pertinent to their immediate interests. Similar types of compendia by physiologists, anatomists, cyberneticists, and psychologists have been helpful to chemists and continue to be so.

Metabolic Reactions in the Nervous System

1 Carbohydrate Metabolism.- 2 Glycogen Metabolism.- 3 Cytochromes and Oxidative Phosphorylation.- 4 Phosphatases.- 5 Peptide Hydrolases.- 6 Biochemistry of Selected Amino Acids.- 7 Metabolism of Aromatic Amino Acids.- 8 Sulfur Amino Acids.- 9 The Nature of ?-Aminobutyric Acid.- 10 Glutamate and Glutamine.- 11 Glycine: Its Metabolic and Possible Transmitter Roles in Nervous Tissue.- 12 Deamination of Nucleotides and the Role of their Deamino Forms in Ammonia Formation from Amino Acids.- 13 Cerebrosides and Sulfatides.- 14 Gangliosides.- 15 Sphingomyelin: Enzymatic Reactions.- 16 Metabolism of Phosphoglycerides.- 17 Metabolism of Phosphoinositides.- 18 Lipid Haptens.- 19 Fatty Acids.- 20 Cholesterol Metabolism.- 21 Metabolism of Myelin Constituents.