This book presents the first comprehensive exploration of the dynamic potential of microtubules anti-cancer targets. Written by leading anti-cancer researchers, this groundbreaking volume collects the most current microtubule research available and investigates the potential of microtubules in cancer therapy.
The Role of Microtubules in Cell Biology, Neurobiology, and Oncology
Table of contents
1. An Overview of Compounds that Interact with Tubulin and their Effects on Microtubule Assembly.
Ernest Hamel
2. Molecular Mechanisms of Micotubule Acting Cancer Drugs.
J. J. Correia and S. Lobert
3. Microtubule Dynamics: Mechanisms and Regulation by Microtubule-Associated Proteins and Drugs in vitro and in cells
Mary Ann Jordan and Leslie Wilson
4. Microtubule Associated Proteins (MAPs) and Microtubule Interacting Proteins: Regulators of Microtubule Dynamics
Maria Kavallaris, Sima Don, Nicole M. Verrills
5. The Post-Translational Modifications of Tubulin
Richard F. Luduena, and Asok Banerjee
6. The Isotypes of Tubulin: Distribution and Functional Significance
Richard F. Luduena, and Asok Banerjee
7. The Tubulin Superfamily
Richard F. Luduena, and Asok Banerjee
8. Tubulin Proteomics in Cancer
Pascal Verdier Pinard, Fang Wang, Ruth Hogue Angeletti , Susan Band Horwitz, and George A. Orr
9. Tubulin and Microtubule Structures
Eva Nogales and Kenneth H. Downing
10. Destabilizing Agents: Peptides and Depsipeptides
Lee M. Greenberger and Frank Loganzo
11. Molecular Features of the Interaction of Colchicine and Related Structures with Tubulin
Susan L. Bane
12. Antimicrotubule Agents that Bind Covalently to Tubulin
Dan L. Sackett
13. Microtubule Stabilizing Agents
Susan Band Horwitz and Tito Fojo
14. Mechanisms of Resistance to Drugs that Interfere with Microtubule Assembly
Fernando Cabral
15. Resistance to Microtubule Targeting Drugs: Part II
Paraskevi Giannakakou and James P. Snyder
16. Microtubule Stabilizing Agent in Clinical Oncology: The Taxanes
Chris H. Takimoto and Muralidhar Beeram
17. Investigational anti-cancer agents targeting the microtubule.
Lyudmila A. Vereshchagina, Orit Scharf, and A. Dimitrios Colevas
18. MicrotubuleDamaging Agents and Apoptosis
Manon Carre and Diane Brauger
19. Microtubule targeting agents and the tumor vasculature
Raffaella. Giavazzi, K. Bonezzi and Giulia Taraboletti
20. Neurodegenerative Diseases: Tau Proteins in Neurodegenerative Diseases Other Than Alzheimer's Disease
André Delacourte, Nicolas Sergeant and Luc Buée
21. Structure, Function and Regulation of the Microtubule Associated Protein Tau
801 777 223
Your basket
