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The articles in this volume cover the various radiosurgical techniques used to treat benign and malignant intracranial tumors, cavernous malformations, and functional disorders, as well as a wide array of specific details on medical physics, neuroimaging, and anesthetic support. Particular emphasis is put on the optimal combination of microneurosurgery and radiosurgery for attaining the best functional results in patients with vestibular schwannomas, craniopharyngiomas, and pituitary adenomas, and on the most effective methods of treatment planning and radiation dosimetry in cases of metastatic brain tumors. The highlighted clinical aspects include indications for radiosurgery and the prediction of patients' prognosis, along with analysis of outcomes in comparison with results achieved by other modalities in the context of multifaceted therapeutic strategies. In addition, possible options for applying advanced treatment using such modern devices as Leksell Gamma Knife Perfexion^TM and Icon^TM are presented in depth. This information will interest both radiosurgical practitioners and neurosurgeons, and help them to provide optimal care and to achieve the greatest benefit of their patients. This book will serve as an excellent companion for the previous publication "Gamma Knife Neurosurgery in the Management of Intracranial Disorders" (Acta Neurochirurgica Supplement, Volume 116, Springer, 2013).

Gamma Knife Neurosurgery in the Management of Intracranial Disorders II

Sponsors ListDedications1. Subtotal Resection Followed by Adjuvant Radiosurgery for Large Vestibular Schwannomas: Outcomes with Regard to Timing and Regimen of Irradiation2. Preplanned Partial Surgical Removal Followed by Low-dose Gamma Knife Radiosurgery for Large Vestibular Schwannomas3. Outcome after Resection of Craniopharyngiomas with Regard to Original Surgical Grading System and Important Role of Stereotactic Radiosurgery in Their Management4. Gamma Knife Radiosurgery of Pituitary Adenomas Invading the Cavernous Sinus: Tokyo Women's Medical University Experience5. Stereotactic Radiosurgery for Pituitary Carcinoma6. Evidence-Based Recommendations for Seizure Prophylaxis in Patients with Brain Metastases Undergoing Stereotactic Radiosurgery7. Cumulative Intracranial Tumor Volume as Prognostic Factor for Patients with Brain Metastases Undergoing Stereotactic Radiosurgery8. Treatment Options for Leptomeningeal Metastases of Solid Cancers: Literature Review and Personal Experience9. Stereotactic Radiosurgery to Prevent Local Recurrence of Brain Metastasis after Surgery: Neoadjuvant vs. Adjuvant?10. Redistributing Central Target Dose Hot Spots for Hypofractionated Radiosurgery of Large Brain Tumors: A Proof-of-Principle Study11. Possible Overcoming Tumor Hypoxia with Adaptive Hypofractionated Radiosurgery of Large Brain Metastases: A Biological Modeling Study12. Differentiating Radiation-Induced Necrosis from Tumor Progression after Stereotactic Radiosurgery of Brain Metastases using Evaluation of Blood Flow with Arterial Spin Labelling (ASL): The Importance of Setting a Baseline13. Gamma Knife Radiosurgery for Symptomatic Cavernous Malformations: Tokyo Women's Medical University Experience14. Gamma Knife Thalamotomy for Medically Refractory Tremor: Longitudinal Evaluation of Clinical Effects and MRI Response Patterns15. Pituitary Radiosurgery for Management of Intractable Pain: Tokyo Women's Medical University Experience and Literature Review16. Feasibility and Significance of Dose Adaptation via Linear Couch Translations to Correct for Rotational Shifts during Frameless Brain Radiosurgery with Gamma Knife Icon(TM)17. Impact of the Skull Size on Normal Brain Radiation Dose during Gamma Knife Radiosurgery: Results of a Pilot Study18. Respiratory Monitoring during Gamma Knife Radiosurgery: Anesthesiological Aspects19. The Proud History of Psychosurgery in the United StatesAuthor IndexSubject Index