For both branches of the adaptive immune system, regulatory molecules i.e. coreceptors and ligands control the signaling cascades initiated by engagement of the T cell and B cell antigen receptors. This book describes these molecules' functions and mechanisms.
Negative Co-Receptors and Ligands
Table of contents
Preface.- TIM-3 and its regulatory role in immune responses.- The role of PD-1 in regulating T cell immunity.- The role of IL-10 in regulating immunity to persistent viral infections. -Inhibitory Ly49 receptors on mouse Natural Killer cells.-Immunoregulatory roles for Fc receptor-like molecules.- Fcgamma Rs in health and disease.- TGF-beta function in immune suppression.- Subject index
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