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Perfusionists are primarily known for supporting patients in the cardiac operating room, while on cardiopulmonary bypass. Over the last decade, perfusionists have expanded their expertise to include extracorporeal membrane oxygenation program development and management, ventricular assist device management, intra-aortic balloon counter pulsation, hemofiltration or dialysis during or post cardiac surgery, pacemaker rogramming, anticoagulation management of HIT-patients, isolated organ perfusion for chemotherapy, and blood gas management. Furthermore, there are additional responsibilities in catheterization laboratories, as well as in research studies and publications. While the roles and responsibilities of a perfusionist can vary from hospital to hospital, the complexity and variety of tasks performed require extensive training and ducation, both in theory and practice.This book is intended to serve as a comprehensive review for perfusionists, surgeons, anesthesiologists, pulmonologists, pediatricians, neonatologists, ICU nurses and ECMO specialists and we believe that it will help to enhance theoretical and practical knowledge and understanding for extracorporeal treatments.

Extracorporeal Circulation in Theory and Practice

Editors and AuthorsPrefaceRudolf Tschaut, Tami Rosenthal, Ashley Walczak, Molly Dreher Introduction to Extracorporeal Circulation in Theory and PracticePedro J. del Nido 1 History of PerfusionThe History of Extracorporeal CirculationWolfgang Böttcher2 Anatomy, Physiology and Interaction of Blood with Artificial Circuits Anatomy and Physiology of the HeartJuan Leon-Wyss, F. Vargas, S.P. Hoerstrup Blood and its ComponentsSergio Picardo, Mario Goracci Interactions of Blood with Artificial Surfaces in the Extracorporeal CircuitSebastian Vogt, Dirk Troitzsch, Stefan Kasseckert, Adrian Bauer3 Anesthesia, Hemodynamics and Acid-Base ManagementAnesthesia Considerations for Cardiopulmonary BypassSteven Bartels, Kathirvel Subramaniam HemodynamicsJorgen Gormsen, Hans Nygaard Monitoring of Cardiovascular Function and Hemodynamics During Extracorporeal CirculationDirk Troitzsch, Sebastian Vogt, Soren Skov, J. Michael Hasenkam Acid-base Management During Hypothermic Cardiopulmonary BypassErvin Severdija Basic Principles of PharmacokineticsHailey Collier, Kerry Mohrien 4 Interventions for Heart Disease Coronary Artery Bypass GraftingJoshua C. Grimm, Wilson Y. Szeto Heart Valve Surgery in AdultsPeter Chen, Stephanie Fuller Transcatheter Aortic Valve Replacement (TAVR)Harald C. Eichstaedt, Alexander WeymannThoracic Aortic Aneurysm and Aortic DissectionDirk Troitzsch, Sebastian Vogt, Georg Kleikamp, Reiner Körfer Heart, Heart-Lung and Lung TransplantationDirk Troitzsch, J. Michael Hasenkam, Gero Tenderich, Reiner Körfer 5 Fluid Mechanics and Hypothermia Fluid Mechanical Aspects in Extracorporeal CirculationHans Reul HypothermiaRobert A. Baker, Kenneth G. Shann 6 Materials and Coating Materials of Extracorporeal CirculationThomas Göen, Frank MünchCoating of Artificial SurfacesElena Barbara Anna Jost, Hans Peter Wendel 7 Extracorporeal Circulation Principles of the Heart-Lung MachineMolly Bryant, Allyson Aquino Pulsatile Flow During Cardiopulmonary Bypass ProceduresAkif Ündar, Shigang WangOxygenators and Heat ExchangersD. Scott Lawson, Daniel Keller Tubing Systems for Cardiopulmonary BypassCarole Hamilton, Denise MarinCannulation Strategies for Extracorporeal CirculationDesiree K. Bonadonna, Richard J. Walczak Jr. Filter Technology in the Extracorporeal CirculationMolly Dreher, Tami Rosenthal, Ashley Walczak Surgical Incisions and Cannulation Techniques for Cardiopulmonary BypassRainer Moosdorf, Sebastian VogtPractical Management of Extracorporeal CirculationLaura Dell'Aiera, Edward Darling, Jeffrey Riley 8 Myocardial Protection Myocardial Protection in Pediatric Cardiac SurgeryChristos Calaritis, Thomas Yeh Advanced Techniques for Myocardial Protection in AdultsLinda B. Mongero, James R. Beck 9 Potential Complications of Cardiopulmonary BypassImmune and Inflammatory Response after CPBKristin C. Greathouse Cardiopulmonary Bypass and the LungChristina Phelps The Effects of Cardiopulmonary Bypass on the KidneyBernadette Chen, Eric A. Lloyd Neurologic Complications of Cardiopulmonary BypassMelissa G. Chung Heparin Induced ThrombocytopeniaDevon Aganga10 Blood ConservationBlood ManagementDavid C. Fitzgerald, Joseph J. Sistino Autotransfusion During Cardiac SurgeryMolly Dreher11 Dialysis and HemofiltrationA Brief Introduction into HemodialysisPeter Kotanko, Vaibhav Maheshwari Special Aspects of Hemofiltration and HemoperfusionFrank Münch Renal Replacement Therapy (CRRT) Applications for ECMOLauren Anderson12 Mechanical Circulatory Support and Pacemaker UseIntra-Aortic Balloon PumpCourtney N. Thurman Mechanical Circulatory Support: Indications, Applications and ComplicationsChristian Heim, M. Weyand, Rene TandlerPacemakers & Implantable DefibrillatorsHarald C. Eichstaedt, Jerry Easo Synchronized Cardiac SupportChristoph Liebetrau, Ivo Simundic, Autumn Lang, Holger Zorn, Alexander Ghanem